Refining a Jagged Edge
نویسندگان
چکیده
منابع مشابه
Jagged Gives Endothelial Tip Cells an Edge
Sprouting blood vessels have tip cells that lead and stalk cells that follow. Benedito et al. (2009) now show that competition between endothelial cells for the tip position is regulated by glycosylation of Notch receptors and by the opposing actions of the Notch ligands Jagged1 and Delta-like 4.
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Here we report the isolation of a rat cDNA clone, Jagged, which we show encodes a ligand for vertebrate Notch. Our conclusion is based on three observations. First, sequence analysis reveals substantial homology between Jagged and invertebrate ligands for the LIN-12/Notch proteins. Second, in situ hybridization of rat embryos identifies both distinct and overlapping patterns of gene expression ...
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Occasionally one may be confronted by a hexahedral or quadrilateral mesh containing doublets, two faces sharing two edges. In this case, no amount of smoothing will produce a mesh with agreeable element quality: In the planar case, one of these two faces will always have an angle of at least 180 degrees between the two edges. We describe a robust scheme for refining a hexahedral or quadrilatera...
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ژورنال
عنوان ژورنال: Structure
سال: 2013
ISSN: 0969-2126
DOI: 10.1016/j.str.2013.11.001