منابع مشابه
Jagged Gives Endothelial Tip Cells an Edge
Sprouting blood vessels have tip cells that lead and stalk cells that follow. Benedito et al. (2009) now show that competition between endothelial cells for the tip position is regulated by glycosylation of Notch receptors and by the opposing actions of the Notch ligands Jagged1 and Delta-like 4.
متن کاملJagged partitions
By jagged partitions we refer to an ordered collection of non-negative integers (n 1 , n 2 , · · · , n m) with n m ≥ p for some positive integer p, further subject to some weakly decreasing conditions that prevent them for being genuine partitions. The case analyzed in greater detail here corresponds to p = 1 and the following conditions n i ≥ n i+1 − 1 and n i ≥ n i+2. A number of properties f...
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Shigella, the causative agent of bacillary dysentery invades intestinal epithelial cells using a type III secretion system (T3SS). Through the injection of type III effectors, Shigella manipulates the actin cytoskeleton to induce its internalization in epithelial cells. At early invasion stages, Shigella induces atypical Ca(2+) responses confined at entry sites allowing local cytoskeletal remod...
متن کاملJagged: A mammalian ligand that activates notch1
Here we report the isolation of a rat cDNA clone, Jagged, which we show encodes a ligand for vertebrate Notch. Our conclusion is based on three observations. First, sequence analysis reveals substantial homology between Jagged and invertebrate ligands for the LIN-12/Notch proteins. Second, in situ hybridization of rat embryos identifies both distinct and overlapping patterns of gene expression ...
متن کاملPillowing doublets: refining a mesh to ensure that faces share at most one edge
Occasionally one may be confronted by a hexahedral or quadrilateral mesh containing doublets, two faces sharing two edges. In this case, no amount of smoothing will produce a mesh with agreeable element quality: In the planar case, one of these two faces will always have an angle of at least 180 degrees between the two edges. We describe a robust scheme for refining a hexahedral or quadrilatera...
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ژورنال
عنوان ژورنال: Structure
سال: 2013
ISSN: 0969-2126
DOI: 10.1016/j.str.2013.11.001